Cantharidin suppresses HCT116 colorectal carcinoma cell proliferation and migration by changing the cytoskeleton structure
نویسندگان
چکیده
منابع مشابه
Downregulation of TMEM40 by miR-138-5p suppresses cell proliferation and mobility in clear cell renal cell carcinoma
Background: Clear cell renal cell carcinoma (ccRCC) represents approximately 70% of RCC,as the most frequent histological subtype of RCC. MiR-138-5p, a tumor-related microRNA (miRNA), has been reported to be implicated in the diverse types of human malignancies, but its role in ccRCCremains unclear. Objective: The study was designed to investigate the function...
متن کاملmiR-29a-3p suppresses cell proliferation and migration by downregulating IGF1R in hepatocellular carcinoma
Hepatocellular carcinoma (HCC), the most common primary tumor of the liver, has a poor prognosis and rapid progression. MicroRNAs (miRNAs) play important roles in carcinogenesis and tumor progression. Insulin-like growth factor 1 receptor (IGF1R) is a transmembrane heterotetrameric protein that has been reported to promote transformation to malignancy and cancer cell proliferation and survival....
متن کاملMiR-144 suppresses cell proliferation, migration, and invasion in hepatocellular carcinoma by targeting SMAD4
BACKGROUND/AIM Increasing evidence show microRNAs (miRNAs) are engaged in hepatocellular carcinoma (HCC). The aim of this study was to investigate the role of miR-144 in HCC, as well as to identify its underlying mechanism. METHODS The expression levels of miR-144 were assessed in multiple HCC cell lines, as well as in liver tissues from patients with HCC. We further examined the effects of m...
متن کاملMiRNA-211 suppresses cell proliferation, migration and invasion by targeting SPARC in human hepatocellular carcinoma
Previous studies have shown that the expression of miR-211 was downregulated in hepatocellular carcinoma (HCC). However, the molecular function and mechanism of miR-211 in HCC growth and invasion are largely unclear. We found that miR-211 is downregulated in HCC tissues and cell lines, respectively. Further results showed that low miR-211 associated with TNM stage, vein invasion status, and poo...
متن کاملMicroRNA-138 suppresses cell proliferation, migration and invasion by targeting smoothened (SMO) in hepatocellular carcinoma
Hedgehog (Hh) signaling pathway is a crucial signal transduction pathway that associated with tumorigenesis in multiple human tissues. Recently, microRNA-138 (miR-138) has been reported to be frequently involved in different tumorigenesis, including hepatocellular carcinoma (HCC). However, whether miR-138 was correlated with Hedgehog (Hh) signaling pathway implicated in the progression of HCC r...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Traditional Chinese Medical Sciences
سال: 2018
ISSN: 2095-7548
DOI: 10.1016/j.jtcms.2018.07.004